The premises, situated on the corner of Adam Street and Port Road in the suburb of Hindmarsh, are to be auctioned on 27 October.
Seven have only occupied the building since 2007 – having moved from their former premises in the suburb of Gilberton where the station had been based since it was launched as SAS10 in 1965 – and buyers are promised a secure 15-year lease to the network.
The studios on site are home to local editions of Seven News and Today Tonight.
The building claims a floor area of 1,887 square metres and is only a light-rail trip from the Adelaide CBD.
The current rent on the property is approximately $643,000 per annum.